- Generic Name or Active Ingridient: Hydrocodone
Zydone detoxification rids the body of toxins accumulated through regular drug use. Zydone detoxification brings a drug-dependent body to a drug-free state.
Zydone is a strong analgesic used to relieve moderate to severe pain, available by prescription only. Most people use Zydone as prescribed and throw away any unused portions. Some people, however, use Zydone non-medically to get high or to treat a condition unrelated to the one the doctor had in mind when she wrote the prescription. About 5 million Americans use painkillers for non-medical use every year. Anyone who uses Zydone regularly for more than a few weeks can develop dependence requiring detoxification, whether he uses Zydone for therapeutic or non-medical reasons.
Zydone contains hydrocodone and acetaminophen. The two medications work in different but complimentary ways to relieve pain. These differences in action make hydrocodone more likely than acetaminophen to produce drug dependence requiring Zydone detoxification. However, dependence on Zydone may cause acetaminophen to accumulate to toxic levels that can result in liver damage, acute liver failure, and other serious complications during Zydone detoxification.
Hydrocodone, Acetaminophen and Zydone Detoxification
Scientists classify hydrocodone as an opioid drug because drug makers create this semi-synthetic pain reliever from extracts of the opium poppy plant. Hydrocodone works like other opioids, including morphine and codeine, to relieve pain by acting directly on the nervous system to change the way the brain interprets pain. The hydrocodone in Zydone causes other neurological effects: sedation, relaxation and euphoria are the most immediately apparent effects. These effects make Zydone attractive to recreational drug abusers.
Other, less noticeable changes alter the consumer’s thoughts, emotions, and behaviors. Prolonged Zydone use makes these alterations more permanent in a way that can adversely affect her ability to work, take care of responsibilities, and interact with others. In time, chronic opioid abuse can result in joblessness, financial crisis, homelessness, divorce or loss of child custody, criminal behavior and incarceration, infectious disease or other illnesses commonly associated with drug abuse, overdose, and death.
Hydrocodone, like other opioids, also act on other body systems to cause physiological effects during periods of drug use and Zydone detoxification. For example, opioids stiffen smooth muscle groups to make certain organs less functional. Hydrocodone stiffens the smooth intestinal muscles that push food through the digestive tract to cause constipation with regular Zydone use; detoxification affects these smooth intestinal muscles resulting in diarrhea during detoxification. Smooth muscles are also located in blood vessel walls to control blood pressure, the skin to produce goose bumps, and in the eyes to contract and dilate pupils; these effects become important during Zydone detoxification.
The acetaminophen in Zydone becomes significant with chronic drug abuse and during detoxification. The body breaks acetaminophen down into smaller metabolites that travel to the liver for processing and elimination. Normally, the liver has no problem clearing these metabolites from the body but it is possible for the liver to fall behind in its work and allow these metabolites to rise to toxic levels. These metabolites are dangerous to the liver, and can actually kill liver cells to cause potentially fatal liver failure.
Acetaminophen overdose is one of the most common poisonings worldwide and is the leading cause of acute liver failure in the United States. Exceeding the recommended total daily dose of 4,000 mg of acetaminophen can lead to serious liver injury in some people. Acetaminophen doses exceeding 7,000 mg can be fatal.
Many people take an accidental acetaminophen overdose after unwittingly consuming multiple acetaminophen-containing products. Acetaminophen is a common ingredient in dozens of prescription and non-prescription drugs: In 2005, Americans purchased more than 28 billion doses of products containing acetaminophen.
Someone can accumulate toxic levels of acetaminophen metabolites by taking a single overdose of acetaminophen or by using large doses of acetaminophen each day, as a Zydone-dependent person might. A person might take an accidental overdose during Zydone detoxification while trying to control uncomfortable withdrawal symptoms.
Zydone Dependence, Detoxification and Withdrawal
The human body acclimates to the presence of some toxic substance, including the hydrocodone in Zydone. In time, the body begins to depend on a certain level of hydrocodone to feel normal - the person becomes opioid-dependent.
When hydrocodone levels fall drastically, the opioid-dependent body struggles to regain chemical balance and eliminate the toxins left behind. Doctors refer to this as Zydone detoxification. The opioid-dependent person experiences this struggle for detoxification through unpleasant physical and psychological withdrawal symptoms that reflect the effects of Zydone on the nervous system and on smooth muscles.
Zydone Withdrawal Symptoms
Withdrawal symptoms associated with Zydone tend to come in two waves with the first set of symptoms appearing within a few hours of the last dose of Zydone.
Early withdrawal symptoms include agitation, anxiety, achy muscles, watery eyes and runny nose, insomnia, profuse sweating and excessive yawning. Later, the patient may develop abdominal cramping, nausea, vomiting and diarrhea, goose bumps and dilated pupils. The patient may experience increased blood pressure and pulse. These withdrawal symptoms reflect the effects of the Zydone detoxification process on the nervous system and smooth muscles located in the digestive tract, cardiovascular system, eyes, and skin.
Withdrawal symptoms persist for five or more days, with the worst symptoms appearing on or about the fourth day. Left untreated and uninterrupted, withdrawal symptoms fade as the body completes the Zydone detoxification process. Withdrawal symptoms do not return unless the body relapses to an opioid-dependent state.
The patient may take medicine to reduce withdrawal symptoms without disrupting Zydone detoxification, such as Imodium to slow diarrhea or vitamin B to soothe muscle aches. He may stop withdrawal symptoms at any time by taking more Zydone, but this halts the detoxification process and returns his body to an opioid-dependent state.
Benefits of Zydone Detoxification
Zydone detoxification is one part of the recovery process - most opioid-dependent people benefit from some amount of rehabilitation to learn how to live without drugs. Zydone detoxification begins to reverse some of the neurological effects of hydrocodone in a way that clarifies the patient’s thinking and helps him make reasonable decisions regarding his recovery.
Additionally, Zydone detoxification ends withdrawal symptoms permanently, which allows the patient to focus on rehabilitation. Detoxification helps the individual remain in rehabilitation long enough to reverse the neurological and physical effects of chronic hydrocodone and acetaminophen abuse. Zydone detoxification begins to repair the patient’s thought processes, emotional health, and behaviors enough to allow him to return to work, reconnect with family, and fulfill his personal responsibilities. Zydone detoxification and rehabilitation restore as much of the patient’s former life as possible.
Zydone detoxification helps the patient feel healthier. This return to good health, clear thinking, and healthy relationships promotes abstinence and reduces the frequency and severity of drug use episodes when they do occur.
Types of Zydone Detoxification
The word ‘detoxification’ also refers to the medical process of lowering opioid levels and relieving withdrawal symptoms. The medical process of detoxification typically includes drugs to ease withdrawal symptoms and professional treatment plans to reduce the occurrence of complications.
About 2 million Americans are dependent on Zydone or other opioids, requiring some form of detoxification to reach an opioid-free state. Only about 10 percent of these individuals will seek help with detoxification from a specialty facility, such as a hospital, outpatient clinic, mental health facility, or a dedicated inpatient detoxification center. Everyone else tried self-care, going to a private physician, getting help from an emergency department, or while in jail or prison.
Every person arrives at an opioid-dependent state in a slightly different way and each individual experiences Zydone detoxification differently too. One person may experience only minor withdrawal symptoms and require a great deal of freedom to work or take care of children during detoxification, for example, while another individual may need a highly structured medical environment to complete Zydone detoxification. Any approach to Zydone detoxification is viable as long as it brings the individual to an opioid-free state safely and efficiently.
When a doctor discontinues Zydone after long-term use, the physician will usually suggest the patient wean himself from this opioid by taking smaller doses each day. This tapering method is appropriate for those who have been opioid-dependent for only a short time, suffer moderate withdrawal symptoms, and are unlikely to have other medical conditions that may cause complications.
Tapering does not always work, especially for patients struggling with stubborn or lingering withdrawal symptoms. These individuals might try “quitting cold turkey” by discontinuing Zydone abruptly in hopes of bearing withdrawal symptoms long enough to complete the detoxification process. Quitting cold turkey usually causes severe withdrawal symptoms.
Some natural remedies ease withdrawal symptoms. Cayenne or chamomile slows diarrhea, for example, while ginger or peppermint soothe an upset stomach. Yoga, meditation, massage, or acupuncture relieves body aches and insomnia.
The Thomas Recipe
The Thomas Recipe is a homemade treatment plan that uses prescription and over-the-counter drugs to relieve withdrawal symptoms during Zydone detoxification. The Thomas Recipe suggests a prescription benzodiazepine, such as Xanax or Librium, for anxiety and sleep problems. This plan also calls for Imodium, vitamin B and hot baths for other withdrawal symptoms.
Medication-assisted detoxification, sometimes called medical detox, uses opioid or non-opioid drugs to control the onset of Zydone detoxification and manage withdrawal symptoms. Many outpatient clinics and inpatient detoxification centers now offer medication-assisted detoxification services that improve someone’s chances for completing the detoxification process.
Outpatient clinics usually offer drug replacement programs that use opioids, like methadone and buprenorphine that mimic the effects of hydrocodone enough to reduce the severity of withdrawal symptoms during the tapering process. At therapeutic levels, these replacement drugs do not get the patient high. Patients start out on a relatively high induction dose during the first few days of treatment then taper methadone or buprenorphine dosages.
Outpatient medical detox is appropriate for patients who have been dependent on Zydone longer than one year, require a great deal of freedom to work during treatment, and are not likely to suffer complications.
A German chemist synthesized methadone for the first time in 1939, in a quest to find a safe and effective opioid pain reliever. Doctors across the globe still prescribe methadone as an analgesic, but U.S. physicians usually reserve methadone for the treatment of substance abuse, most notably heroin addiction.
About 100,000 Americans use a methadone maintenance program, which uses methadone to delay the onset of detoxification while the patient participates in treatment. The patient comes to an outpatient clinic each day to drink a beverage containing methadone. When the individual has gained the tools he needs to lead a drug-free life, he tapers methadone or participates in methadone detoxification.
Today, many outpatients offer methadone as an aide to tapering. Patients start out on an induction dose of 10 to 15 mg of methadone. The outpatient clinician may increase daily dosages in 10 mg increments to control stubborn withdrawal symptoms. Once the clinician establishes a safe induction dose, the patient slowly tapers methadone dosages until achieving an opioid-free state.
An outpatient clinic may prescribe buprenorphine to be used as part of a drug maintenance program or as an aid to tapering. Buprenorphine is a sublingual medication; the patient places a buprenorphine tablet under his tongue where it dissolves and enters the bloodstream at the appropriate rate. It is possible to abuse buprenorphine intravenously by dissolving the tablet before injecting the drug into a vein.
Suboxone is a buprenorphine preparation that also contains naloxone. When used sublingually, naloxone has no effect on the consumer. Intravenous naloxone use, however, neutralizes the effects of buprenorphine so the consumer does not get high. Furthermore, naloxone causes withdrawal symptoms in an opioid-dependent user.
Many hospitals and other inpatient facilities now offer medication-assisted detoxification. These inpatient institutions use non-opioid, medical grade drugs to lower hydrocodone levels and reduce withdrawal symptoms. Inpatient medical detox usually includes prescreening to detect any underlying conditions that may cause complications and close patient monitoring to address any complications that do arise.
Inpatient Zydone detoxification is appropriate for anyone who suffers severe withdrawal symptoms or have an illness that increases the risk for complications. Inpatient care is right for anyone who has had limited success with less restrictive approaches.
Anyone recovering from an overdose must continue detoxification in a hospital or other inpatient setting. Inpatient Zydone detoxification is appropriate for those with serious psychiatric problems that interfere with care, such as acute psychosis or depression with suicidal thoughts.
Rapid Zydone Detox
Rapid opiate detox is a safe and effective procedure that rids the body of hydrocodone while the patient sleeps. During rapid detox, anesthesiologists sedate and anesthetize the patient so he rests in a comfortable “twilight sleep” during the difficult Zydone detoxification process. The patient awakens a few hours later, unaware of the grueling withdrawal symptoms that may have prevented success in the past.
Our detoxification center: Who we are and what we do
We are a group of medical professionals dedicated to helping people reach an opioid-free state. Our board-certified anesthesiologists receive advanced training in detoxification procedures and specialize in rapid detox. We have helped thousands of patients detoxify their bodies from the toxic effects of Zydone and other opioids since opening the doors of our fully accredited hospital more than a decade ago.
We start by prescreening patients for any illnesses that may cause complications during Zydone detoxification. We then develop a personalized treatment plan that may include rapid detox. After the patient completes detoxification, he may choose to continue recovery efforts in our qualified aftercare facility.
Comparisons of the Various Approaches to Zydone Detoxification
Opioid dependence is often traumatic and confusing. Choosing between the various forms of Zydone detoxification can be intimidating. Comparing the different treatment plans can be helpful, as comparisons highlight the benefits and disadvantages of each approach.
Self-detoxification brings the patient to an opioid-free state in a moderate amount of time as compared to outpatient and inpatient Zydone detoxification. Self-detoxification is the least costly approach because it usually does not include prescreening, anti-withdrawal drugs, professional treatment plans or patient monitoring. However, the lack of these services increases the risk for severe withdrawal symptoms and complications during self-detoxification.
Outpatient care that includes opioid replacement drugs is associated with less severe withdrawal symptoms and fewer complications than self-detoxification, but using opioid drugs can sometimes slow the tapering process. Patients may remain in treatment for weeks or months. Furthermore, outpatients are more likely to become dependent methadone or buprenorphine, whereas those who try self-detoxification or inpatient care are not likely to become dependent on the drugs used in those procedures.
Inpatient care is associated with the least severe withdrawal symptoms and risk for complications. Inpatient care delivers the patient to an opioid-free state in a relatively short time: the average length of stay for detoxification is 4 days, compared with 197 days for medication-assisted therapy.
Rapid detox is the most efficient approach, offering the fastest approach to complete Zydone detoxification. Rapid detox patients achieve an opioid-free state in hours rather than days, weeks or months. Rapid detox is also the most humane treatment for opioid dependence, as it spares patients the painful and demoralizing withdrawal symptoms associated with other forms of Zydone detoxification.
Possible Complications during Zydone Detoxification
While Zydone detoxification is not a life-threatening process, severe withdrawal symptoms and certain medical conditions can cause complications. All forms of detoxification can cause pain to return in patients who take Zydone to relieve discomfort associated with an illness, injury, or invasive medical procedure.
Relapse is the chief complication associated with all forms of Zydone detoxification. Someone can relapse during detoxification to stop withdrawal symptoms, or sometime after reaching an opioid-free state. A sustained relapse returns the patient to an opioid-dependent state and increases the risk for overdose.
The detoxification process makes the body more sensitive to the effects of hydrocodone, meaning it takes less Zydone to achieve the same effects. This increased sensitivity makes it possible for someone to overdose on a smaller amount of Zydone that he took just hours before experiencing even minor withdrawal symptoms.
Overdose can be fatal. In 2008, overdoses from Zydone and other opioids claimed the lives of 14,800 people in the United States. That year, for the first time in U.S. history, more people died from prescription drug overdose than from overdoses from cocaine and heroin combined.
Self-Detoxification Possible Complications
Extreme vomiting or diarrhea can cause dehydration and dangerous imbalances in potassium, sodium, and other electrolytes. Zydone detoxification can increase blood pressure, pulse, and perspiration, potentially aggravating some types of heart conditions. The detoxification process can worsen anxiety in patients with pre-existing mood disorders.
Patients may accidently take an acetaminophen overdose during Zydone detoxification because they are unaware of potentially toxic metabolite levels resulting from chronic Zydone consumption. The symptoms of an acetaminophen overdose are often similar to Zydone withdrawal symptoms, causing the patient to continue taking even more acetaminophen to control that discomfort. Furthermore, the signs and symptoms of acetaminophen overdose may not appear for several hours or a few days, increasing the risk for toxic overdose even more.
Outpatient Care Possible Complications
Some outpatients have a hard time quitting opioid replacement drugs used to ease tapering, and remain on methadone or buprenorphine for months or years. A few remain on opioid replacement drugs for the rest of their lives.
Methadone and buprenorphine are not entirely safe. Methadone accounts for about one-third of opioid pain reliever deaths, even though methadone sales account for only 2 percent of the prescription painkiller market. The number of deaths associated with methadone is increasing: in 2009, there were 5.5 times as many methadone-related deaths as there were in 1999.
While many medical professionals consider buprenorphine safer than methadone, there is still risk for overdose. Death is possible, especially for those who combine buprenorphine with benzodiazepines such as those used in The Thomas Recipe.
Inpatient Detox Possible Complications
Inpatient care provides great protection from complications but patients may still suffer obstacles to recovery. Withdrawal from multiple substances, especially alcohol, benzodiazepines, sedatives and anti-anxiety drugs may complicate inpatient Zydone detoxification.
Rapid Detox Possible Complications
Rarely, someone may suffer an allergic reaction to the drugs used in rapid detox. Strong sedatives may complicate breathing, blood pressure, and heart rate. A patient may develop swelling, bruising, or an infection at the anesthesia injection site.
Myths about Zydone Detoxification
Scientists have spent decades studying the toxic effects of opioids and gathering information about detoxification. Despite the wealth of data about detoxification, myths about treatment prevent some people from getting the help they need to achieve an opioid-free state. Dispelling these myths can make the detoxification process easier to understand and control, reducing withdrawal symptoms and complications and increasing the likelihood the individual will complete the Zydone detoxification process.
Self Detox Myths
Myth: Self-detoxification is not life threatening, which means it is always safe for everyone.
Fact: It is true that self-detoxification is not usually fatal, but withdrawal symptoms and underlying illnesses can cause dangerous complications for some people. These complications may become serious or even life threatening in some cases.
Myth: The Thomas Recipe makes self-detoxification safe for everyone because it uses prescription and non-prescription drugs to reduce withdrawal symptoms and complications.
Fact: Combining prescription and non-prescription medications can result in dangerous drug interactions, especially in the presence of high hydrocodone and acetaminophen levels.
Outpatient Detox Myths
Myth: It is cheaper to imprison drug abusers than to provide methadone.
Fact: Treatment is cheaper than incarceration. One year of methadone costs an average of $4,700 per patient; that same year of imprisonment costs taxpayers about $24,000 per prisoner.
Myth: Methadone causes bone rot.
Fact: Inadequate methadone dosages can cause withdrawal symptoms, including deep aches that can feel like the bones are rotting. Any methadone patient suffering bone ache should discuss a dosage increase with the prescribing clinician.
Inpatient Detoxification Myths
Myth: Treating drug addiction at a hospital is a waste of space - addiction is an incurable disease.
Fact: Drug addiction and dependence are chronic illnesses and have relapse rates similar to those of other chronic diseases, such as high blood pressure, diabetes or asthma - about 40 to 60 percent. Furthermore, all people deserve competent and compassionate medical care, even if they suffer a chronic condition with poor relapse rates.
Myth: Communities cannot afford to provide drug treatment in a bad economy.
Fact: Drug treatment is a worthwhile investment for communities. Experts estimate every dollar spent on drug treatment programs returns a yield between $4 and $7 in reduced drug-related crime rates, criminal justice costs and theft. When these experts add in healthcare costs associated with dependence, a community can expect a return of $12 gained for each dollar invested.
Rapid Detox Myths
Myth: Detox always involves suffering.
Fact: Rapid detox is a humane approach to medical detoxification. Rapid detox patients enjoy a pleasant twilight sleep instead of enduring endless days of detoxification.
Myth: Complete Zydone detoxification takes weeks or months.
Fact: Rapid detox brings patients to an opioid-free state in hours.
Zydone Detoxification and Pregnancy
Dependence on Zydone or other opioids increases the risk a woman will develop certain medical conditions that can complicate pregnancy, endangering the health of the woman and her unborn baby during pregnancy, labor, and delivery. Complications include slowed fetal growth, hemorrhage, separation or inflammation of the tissues surrounding the baby, spontaneous abortion, premature labor and delivery, and fetal death.
Complications may make detoxification unsafe for pregnant women. Methadone reduces these complications and is currently the only approved treatment plan for opioid-dependent women.
A baby born to a woman who uses Zydone, methadone, buprenorphine, or other opioids during pregnancy may be born with neonatal abstinence syndrome, or NAS. A baby born with this condition is likely to suffer withdrawal symptoms during the first weeks or months of life. NAS babies often struggle with low birth weight, feeding difficulties, seizures, and death.
Self Detox and Pregnancy
Self-detoxification may be unsafe for a pregnant woman and her unborn baby. A pregnant woman should consult with a physician before attempting even a moderate tapering program.
Inpatient Induction to Methadone Maintenance during Pregnancy
A physician will likely admit a pregnant woman to a hospital to initiate methadone treatments. He will usually start her on 10 mg to 20 mg of methadone for the first day. Based on her response to treatment, the physician might increase the next day’s dosage an additional 5 - 10 mg. He will continue to increase dosages slowly until he finds a safe dosage that still controls her withdrawal symptoms, with a maximum of 60 mg of methadone daily.
Inpatient care usually includes fetal monitoring to gauge the baby’s response to treatment. The mother can expect to stay in the hospital about 3 days. The hospital will discharge the mother to outpatient care.
Outpatient Induction to Methadone Maintenance during Pregnancy
A woman may be unable or unwilling to start methadone as an inpatient and choose to start treatment as an outpatient. This patient will come to the outpatient clinic twice daily, once for a daily dose of methadone and again later for evaluation. Once the clinician establishes a safe and effective maintenance dose, the woman may reduce her visits to the clinic to once a day.
Women using methadone to maintain opioid dependence may suffer withdrawal symptoms late in pregnancy and require larger doses of methadone. The outpatient clinician will adjust dosages accordingly, and continue treating the mother until delivery.
Babies born to women taking methadone during pregnancy will remain under close observation for signs of NAS for 72 hours after delivery.
What is the best method of Zydone detoxification?
Everyone has different needs when it comes to Zydone detoxification - one person might have minor withdrawal symptoms and require a great deal of freedom while another individual may suffer serious discomfort and require close supervision. An individual should assess his own likelihood for withdrawal symptoms and complications, along with his ability to abstain from drug use, then choose the least restrictive approach to treatment that is still likely to bring him to an opioid-free state in a safe and effective manner.