Vicoprofen is a combination hydrocodone and ibuprofen. Doctors prescribe Vicoprofen for short-term, severe pain. Vicoprofen is not recommended for arthritis pain. Learn More About Vicoprofen Uses


Each Vicoprofen table contains 7.5 mg hydrocodone and 200 mg ibuprofen. The typical prescription for short term pain management, typically given for ten days or less, is for one Vicoprofen tablet every four to six hours as necessary for pain. You should not exceed five tablets in a 24 hour period. Dose and frequency is adjusted according to the patient's need, starting with the smallest dose possible to provide pain coverage. Tolerance to Vicoprofen can increase with prolonged use. The incidence of unfavorable effects is dose-related; the patient should remain on the lowest dose possible. Physicians should remain alert to signs of increased tolerance and dependence.

Vicoprofen is normally prescribed to be taken as needed for pain; do not worry if you miss a dose. Simply take another dose when you have pain, provided enough time has passed since your last dose. If you are taking Vicoprofen on a regular schedule and miss a dose, take another dose as soon as you remember. If it is nearly time to take a regularly scheduled dose, skip the missed dose and resume your normal schedule. If you miss several consecutive doses, or if you have trouble maintaining the prescribed schedule, talk with your doctor. Read More About Vicoprofen Administration and Dosage


The two active ingredients in Vicoprofen, hydrocodone and ibuprofen, work in different ways to provide complete pain relief. Hydrocodone binds to the receptor cells in the brain and nervous system, changing the way the brain perceives pain. Ibuprofen works by reducing hormones that cause pain and inflammation. More About How Vicoprofen Works


Tell your doctor if you are allergic to the components of Vicoprofen, hydrocodone or ibuprofen, or any other medication. Notify your physician if you have ever experienced an allergic reaction to other narcotic pain relievers such as codeine or morphine. Give your doctor and pharmacist a list of all your allergies; you may be allergic to additives to Vicoprofen. An allergic reaction is a serious, potentially life-threatening medical emergency. Seek immediate help if you experience an allergic reaction shortly after taking Vicoprofen. Symptoms of an allergic reaction include hives, difficulty breathing and swelling of your face, lips, tongue or throat.

You may not be able to take Vicoprofen if you have a history of certain medical conditions. Tell your doctor about any serious or chronic illnesses including aspirin-sensitive asthma, which is worsening breathing with a runny or stuffy nose after taking aspirin or other NSAIDs. Notify your physician and pharmacist if you have had a personal history of anemia, bleeding or clotting problem, brain disorders such as head injury, tumor, seizures, stroke or breathing problems.

Other medical conditions may prevent you from taking Vicoprofen. Tell your doctor if you have ever had heart disease, congestive heart failure, high blood pressure, or a history of heart attack, stroke or blood clot. Talk with your physician about asthma or other breathing disorders, liver or kidney disease. Do not take Vicoprofen if you have ever had a stomach or intestinal disorder, history of stomach ulcer or bleeding. Notify your physician if you have ever been diagnosed with an underactive thyroid, Addison's disease or other adrenal gland disorder, or curvature of the spine. Tell your healthcare provider if you have an enlarged prostate or problems with urination.

Vicoprofen can cause constipation. Drink six to eight full glasses of water each day to soften stools and reduce constipation. Increase your intake of dietary fiber, known to be beneficial your digestive system.

Vicoprofen can impair your thinking and decision-making. Do not operate heavy machinery or engage in any behavior that requires you to be alert and awake. Alcohol and some over-the-counter medications can enhance this effect.

Do not consume alcohol while taking Vicoprofen. Drinking alcohol increases your risk for serious stomach bleeding.

This drug can be habit-forming, especially if you take it for long periods of time. Tell your doctor if you have a history of dependence or addiction to drugs or alcohol. Your physician may choose a different course of treatment or adjust your dosage accordingly.

Read More About Vicoprofen Precautions


Ibuprofen can increase your risk for heart attack or stroke. Do not use Vicoprofen just before or immediately after heart bypass surgery, also known as coronary artery bypass graft, or CABG. Seek emergency help if you experience chest pain, weakness, shortness of breath, slurred speech or problems with vision or balance after taking Vicoprofen. Ibuprofen also increases your risk for serious effects on your stomach or intestines. These conditions may come on suddenly and unexpectedly and can be serious or fatal. Go to the emergency room or call for an ambulance immediately if you have black, bloody, or tarry stools or if you cough up blood or vomit that looks like coffee grounds. Drinking alcohol while taking Vicoprofen can increase your risk for stomach bleeding. Vicoprofen may affect your unborn baby. Taking Vicoprofen in the last three months of pregnancy may harm your baby. Tell your doctor if you are pregnant or plan to become pregnant while taking Vicoprofen. If you become pregnant while taking Vicoprofen, call your doctor immediately. Vicoprofen can be passed into breast milk. Do not take Vicoprofen while breastfeeding.

Don't stop taking Vicoprofen suddenly; doing so may cause unpleasant withdrawal symptoms. Try weaning yourself from Vicoprofen by taking smaller doses less frequently. If withdrawal symptoms prevent you from quitting Vicoprofen, talk with your doctor or qualified in-patient or out-patient rehabilitation center. More Warnings About Using Vicoprofen

Drug Interactions

Vicoprofen may interact in an unfavorable or even dangerous way with other prescriptions, over-the-counter medications and herbal remedies. Give your doctor a complete and updated list of medicines. Be sure to tell your doctor if you take ACE inhibitors for high blood pressure, antidepressants, aspirin, antihistamines, antipsychotics or medicine for anxiety.

More Drug Interactions

Side effects

You may experience side effects while taking Vicoprofen. If side effects become acute or don't go away on their own, talk with your doctor. Some side effects can be severe or life-threatening. Seek medical assistance immediately if you experience severe side effects such as chest pain, weakness, and shortness of breath, slurred speech, and problems with vision or balance. Other serious side effects include sudden numbness or weakness, headache, confusion, or problems with vision, speech, or balance. Go to the emergency room if you experience black, bloody, or tarry stools or start coughing up blood.

Learn More About Vicoprofen Side Effects


Vicoprofen overdose is a serious, life-threatening medical emergency. If you suspect that you or someone you know has taken an overdose of Vicoprofen, seek emergency assistance immediately by going to the emergency room or calling an ambulance. If you are a very long distance from professional help, contact your local poison control center at 1-800-222-1222. Overdose symptoms include extreme drowsiness, nausea or vomiting. Seek help immediately if you pas dark urine or notice yellowing of the skin or eyes, a condition known as jaundice. Go to the emergency room or call for an ambulance if you have black or bloody stools, are coughing up blood or urinating less than usual or not at all. More symptoms of overdose include confusion, ringing in your ears, pinpoint pupils, weak pulse, slow heart rate, blue lips, shallow breathing or fainting.

Learn More About Vicoprofen Overdose


Vicoprofen is a Schedule III drug, which means abuse may lead to moderate or low physical dependence or high psychological dependence. Do not take Vicoprofen after your pain has subsided. Do not share Vicoprofen with others. Read More About Vicoprofen Abuse


Withdrawal is not necessarily a sign of willful substance abuse. Withdrawal is a normal, predictable, physical sign of dependency. Withdrawal symptoms may appear after you stop taking Vicoprofen, especially if you have been taking high doses or using the opioid for a long period of time. Talk with your doctor if you have trouble quitting Vicoprofen. More About Vicoprofen Withdrawal


You may need the help of qualified professionals to help you detoxify your body from Vicoprofen. Strong withdrawal symptoms may make dependency and addiction to Vicoprofen difficult to overcome on your own. Quitting may be more difficult if you have been taking large doses or using opioids for a long time. Talk with your doctor or seek in-patient and out-patient treatment facilities where trained professionals can minimize withdrawal symptoms, detoxify your body and give you the tools you need to live drug-free. Detoxification, rehabilitation and counseling are effective therapies to treat addiction to Vicoprofen and other opiates.

Learn More About Vicoprofen Detoxification Programs


Keep Vicoprofen in a safe place, away from children, pets and adults who might consume this product willfully or accidentally. Store Vicoprofen away from excessive heat and moisture. Never share Vicoprofen or other opioids with others, especially with people with a history of alcohol or drug abuse. Keep track of your medication, taking note of any missing doses.

Read More About Storing Vicoprofen