Roxicodone is a narcotic pain reliever used to treat moderate to severe pain. It may be used before surgery to calm and sedate the patient, reducing fear and anxiety. Roxicodone is not normally given to reduce post-operative pain unless the patient was already taking this narcotic to relieve pain. Learn More About Roxicodone Uses


Roxicodone is available in tablet form to be taken by mouth. The usual adult dose is 10 to 30 mg every four hours as needed for pain. Your doctor may start you on a lower dose and increase strength to provide sufficient coverage. You may need to take increasingly stronger doses as you build tolerance to opiates.

The safety and effectiveness of Roxicodone for children has not been established. Discuss the benefits and risks of Roxicodone with your child's pediatrician.

Roxicodone is typically prescribed to be taken on an as-needed basis whenever you feel pain. As such, you don't have to worry about missing doses. If your doctor told you to take Roxicodone on a regular schedule and you missed a dose, take another dose as soon as you can. However, if it is nearly time to take another tablet, skip the missed dose and resume your regular schedule. Do not take extra Roxicodone in an effort to make up for missed doses. Read More About Roxicodone Administration and Dosage


The precise pain-relieving action of Roxicodone is not known but scientists believe this drug works by interacting with the brain and spinal cord in a way that changes the way the brain perceives pain. A positive attribute of opioids is that this class of drugs provide pain relieve without loss of consciousness. Additionally, morphine-like opioids reduce pain without interfering with vision, hearing, etc. Roxicodone causes respiratory depression, or shallow and slow breathing. Oxycodone is the active ingredient in Roxicodone. Oxycodone causes respiratory depression by acting directly on the respiratory center in the brain stem. Oxycodone suppresses the cough reflex by direct action on the cough center in the medulla, located low in the brain stem. More About How Roxicodone Works


Tell your doctor if you are allergic to Roxicodone or any other medication, especially if you have ever experienced an allergic reaction to another narcotic. Seek immediate medical assistance if you have any symptoms of an allergic reaction, including hives and swelling of the face, lips and tongue.

You may not be able to take Roxicodone if you have had certain medical conditions, like brain disorders, breathing problems, liver or kidney disease, and intestinal problems. Talk with your doctor if you have ever had a head injury, tumor or seizures. Discuss your history of asthma, sleep apnea or chronic obstructive pulmonary disease, known as COPD. Your physician should know of any personal or family history of regular use or abuse of drugs or alcohol before you take Roxicodone. Tell your doctor if you have ever had digestive or urinary problems, such as blockage, constipation, diarrhea due to infection, paralytic ileus or difficulty urinating. Roxicodone may worsen these conditions.

Roxicodone may make you drowsy. Do not drive a car or operate heavy machinery until you know how your body reacts to Roxicodone. Avoid risky behaviors or activities that require you to be alert or awake.

Do not consume alcohol while taking Roxicodone. Drinking alcohol may worsen side effects.

This drug can be habit-forming, especially if you take it for long periods of time.

Read More About Roxicodone Precautions


It is not known if Roxicodone can harm your unborn baby. Your physician will weigh the benefit of using Roxicodone against the potential risk to the unborn baby. Tell your doctor if you are pregnant or plan to become pregnant while taking Roxicodone. Notify your physician if you become pregnant while taking Roxicodone. Roxicodone has been found in breast milk; do not take Roxicodone while breastfeeding your child.

Stopping Roxicodone use suddenly may cause unpleasant withdrawal symptoms. Whenever possible, wean yourself from Roxicodone by taking smaller doses further apart. If you cannot comfortably stop using Roxicodone, consult with your doctor or qualified in-patient or out-patient rehabilitation center. More Warnings About Using Roxicodone

Drug Interactions

Tell your doctor about all medications, including prescriptions, over-the-counter and herbal remedies. Some drugs interact in unfavorable or even dangerous ways with Roxicodone. Do not take Roxicodone with other muscle relaxants, as this increases the risk for dangerous respiratory depression. Avoid taking Roxicodone with other narcotic analgesics, general anesthetics, tranquilizers, sedatives or alcohol. Doing so may result in dangerous effects, such as respiratory depression, hypotension, profound sedation or coma. Pentazocine, nalbuphine, butorphanol and buprenorphine can reduce the analgesic effects of Roxicodone and may cause withdrawal symptoms. Do not take Roxicodone if you have taken MAO inhibitors within the past 14 days. Taking Roxicodone before MAO inhibitors have cleared your system may result in anxiety, confusion, significant respiratory depression or coma.

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Side effects

You may experience side effects while taking Roxicodone. Seek emergency medical assistance if you experience serious side effects, as this is a life-threatening medical condition.

Serious side effects include:

  • Shallow Breathing.
  • Slow Heartbeat.
  • Seizures.
  • Cold, Clammy Skin.
  • Confusion.
  • Severe Weakness.
  • Dizziness.
  • Feeling Light-headed.
  • Fainting.

You may experience less serious side effects. Talk with your doctor if these symptoms become severe or if they don't subside on their own. Less serious side effects include nausea, constipation, vomiting, headache and itching. Learn More About Roxicodone Side Effects


If you suspect that you or someone you know has taken an overdose of Roxicodone, seek emergency assistance immediately. Contact your local poison control center at 1-800-222-1222 or go to the emergency room. Overdose symptoms include:

  • Difficulty Breathing
  • Slowed or Stopped Breathing.
  • Excessive Sleepiness.
  • Dizziness.
  • Fainting.
  • Limp or Weak Muscles.
  • Increase or Decrease in Pupil Size.
  • Cold, Clammy Skin.
  • Slow or Stopped Heartbeat.
  • Blue Color of Skin, Fingernails, Lips or Area around the Mouth.
  • Loss of Consciousness or Coma.

Learn More About Roxicodone Overdose


Roxicodone is a Schedule II drug, which means it carries a significant risk for abuse and physical as well as psychological dependence. Pharmaceutical companies legally manufacture Roxicodone for licit use as a pain reliever but abusers obtain Roxicodone through forged prescriptions, bogus prescription call-ins to pharmacies, "doctor shopping" as well as theft from pharmacies and friends. Read More About Roxicodone Abuse


You may experience unpleasant withdrawal symptoms when you stop taking Roxicodone, especially if you have been using high doses or taking the opioid for a long period of time. Symptoms vary in intensity. Withdrawal is a normal, predictable, physical sign of dependency, not necessarily a sign of willful abuse. Withdrawal symptoms may prevent you from quitting Roxicodone without medical assistance. Withdrawal symptoms include restlessness, watery eyes, runny nose, sneezing, yawning, sweating, chills, muscle or joint aches or pains, weakness, irritability, anxiety, depression, difficulty falling or staying asleep, cramps, nausea, vomiting, diarrhea, loss of appetite, fast heartbeat, and fast breathing.


Dependency and addiction to Roxicodone is often difficult to overcome on your own, especially if you have been taking large doses or using these opioids for a long time. Fortunately, there are in-patient and out-patient treatment facilities where trained professionals can minimize withdrawal symptoms, detoxify your body and give you the tools you need to live drug-free. Detoxification, rehabilitation and counseling are effective therapies to treat addiction to Roxicodone and other opiates.

Learn More About Roxicodone Detoxification Programs


Keep Roxicodone away from excessive heat and moisture. Do not keep this drug in your bathroom or car. Store Roxicodone away from children, pets and adults who might accidently or purposefully consume the drug. Do not share Roxicodone with others, especially with individuals with a history of alcohol or drug abuse. Keep track of your medication, taking note of any missing doses.

Read More About Storing Roxicodone