Percodan-Demi Detox

Percodan-Demi detoxification brings a person’s body to a drug-free state. Detoxification reverses some of the negative effects chronic Percodan-Demi use has on the body.

Percodan-Demi is available only by prescription. Percodan-Demi contains oxycodone and aspirin. Despite this restricted status, oxycodone is widely available: U.S. pharmacists dispensed 58.2 million prescriptions for Percodan-Demi and other drugs containing oxycodone in 2010.

Most people use Percodan-Demi as prescribed and stop using this drug when they no longer need it to control pain. Some people, however, use Percodan-Demi for non-medical reasons either to get high or to treat a different condition than the prescribing physician had intended to treat. About 5 million Americans use Percodan-Demi and other painkillers for non-medical use every year.

Oxycodone is an opioid drug, made from ingredients derived from the opium poppy plant. A doctor prescribes Percodan-Demi to relieve a patient’s moderate to severe pain. Like other opioids, the oxycodone in Percodan-Demi works directly on the nervous system to change the way the brain perceives pain signals. Among other neurological effects, oxycodone causes sedation, relaxation and a pleasant euphoric feeling.

With continued Percodan-Demi use, some of the neurological changes become more permanent, altering the individual’s thoughts, behaviors, and emotions. These alterations can have a profoundly negative impact on the person’s ability to work, go to school, take care of family, and interact with others.

Opioids, including the oxycodone in Percodan-Demi, work with other body systems to produce different effects in the body. Most notably, opioids affect smooth muscle groups. These smooth muscles are located in different areas of the body, including intestinal muscles that push stool through the digestive tract, those muscles inside blood vessel walls that control blood pressure, the muscles that make the pupils of the eyes grow large and small, and those muscles just below the surface of the skin that make goose bumps appear.

The human body is resilient, adapting to presence of some substances like the oxycodone in Percodan-Demi. With continuous use, the body grows dependent on a certain level of oxycodone to feel normal - the individual has become opioid-dependent.

Anyone who uses Percodan-Demi regularly for more than a few weeks can become opioid-dependent, whether he uses this medication for therapeutic or non-medical reasons. According to results from a 2011 national survey, about 1.9 million people in the U.S. are dependent on prescription painkillers such as Percodan-Demi. This number has grown slightly since 2004, when there were 1.4 million opioid-dependent Americans.

When oxycodone levels fall abruptly, the opioid-dependent body struggles to adapt to these lowered opioid levels and recover from the toxic effects of oxycodone. Doctors refer to this as Percodan-Demi detoxification. The opioid-dependent person experiences Percodan-Demi detoxification through unpleasant, flu-like symptoms.

Withdrawal symptoms begin a few hours after the last dose of Percodan-Demi. Left uninterrupted, withdrawal symptoms last five or more days, fading as the patient completes the detoxification process. Withdrawal symptoms do not return unless the individual again becomes opioid-dependent.

Someone can reduce individual withdrawal symptoms with medications or herbal remedies. He can also stop withdrawal symptoms at any time by taking more Percodan-Demi, but this relapse reverses the effects of detoxification and returns him to an opioid-dependent state.

Detoxification can also refer to the medical procedure of administering drugs to lower opioid levels plus medications to ease withdrawal symptoms. This type of detoxification can take place at home, through an outpatient clinic, a hospital, or specialized detoxification facility.

Detoxification brings an opioid-dependent person to an opioid-free state but, by itself, does little to change the behaviors associated with drug abuse. Most opioid-dependent people benefit from rehabilitation, where they learn how to live without drugs. Rehabilitation usually includes counseling and behavior modification that teaches the individual how to identify situations that may lead to drug abuse and how to refuse Percodan-Demi when offered.

Percodan-Demi detoxification facilitates the patient’s entry into rehabilitation and helps them remain there long enough to reverse some of the neurological changes caused by drug abuse, and restore the patient’s thought processes, behaviors and emotional well-being. Detoxification and rehabilitation help the individual return to his former life - working, taking care of family, and interacting with others.

Percodan-Demi detoxification promotes abstinence and reduces the frequency and severity of drug use episodes when relapses do occur.

Types of Detox

While Percodan-Demi causes predictable neurological, physical, behavioral, and social changes in an individual, each opioid-dependent person experiences his condition in a slightly different way. One person might be opioid-dependent for only a few weeks after taking Percodan-Demi after surgery and feels only mild withdrawal symptoms, for example, while another may suffer severe symptoms while attempting detoxification after chronic, recreational Percodan-Demi use.

No single treatment plan is right for everyone. Additionally, someone might have to try several treatment approaches throughout the course of this chronic neurological illness.

Of those who need treatment for substance abuse problems such as Percodan-Demi dependence, only about 10 percent got it at an inpatient hospital, outpatient clinic, mental health institution, or other specialty facility. Everyone else tried self-detoxification, worked with a private physician, sought help in an emergency room, or completed detoxification while incarcerated in jail or prison.

Self Detox

Self-detoxification usually takes place at home. When a patient takes Percodan-Demi for longer than a few weeks, his physician will suggest he taper Percodan-Demi by taking a smaller dose each day - just enough to stop withdrawal symptoms - until he completes the detoxification process. Someone who has become dependent on Percodan-Demi through recreational drug abuse should try self-detoxification first as long as he does not have any pre-existing conditions or co-existing substance abuse issues that could cause complications.

Cold turkey

The tapering method works well for many people but stubborn withdrawal symptoms prevent some people from weaning themselves from Percodan-Demi. These individuals might be tempted to quit cold turkey by discontinuing Percodan-Demi abruptly.

Without anti-withdrawal drugs, someone who quits cold turkey experiences severe and prolonged withdrawal symptoms that can be both uncomfortable and demoralizing. The phrase “cold turkey” refers to the skin’s poultry-like appearance during Percodan-Demi detoxification: pale, cold, and clammy with goose bumps.

If the individual can withstand the withdrawal symptoms long enough, quitting cold turkey does bring him to an opioid-free state.

Natural remedies

Many people hope to improve the detoxification experience through natural remedies, eating certain herbs, vegetables, juices or soups. Someone might eat ginger or peppermint to ease nausea, for example, or take chamomile or cayenne to curb diarrhea. Another person might try acupuncture, meditation, yoga, or massage to bolster his body’s response to Percodan-Demi detoxification.

Some individuals take a medical approach to home detoxification by developing a treatment plan that includes prescription and over-the-counter drugs to ease withdrawal symptoms. One well-known homemade treatment plan is The Thomas Recipe, which calls for a benzodiazepine such as Xanax or Librium to calm nerves and help with sleep, Imodium for diarrhea, vitamin B6 with hot baths for restless leg syndrome and muscle aches, and a shot of L-Tyrosine for a much-needed burst of energy during the later stages of Percodan-Demi detoxification.

Medical Detox

Most patients benefit from medical detoxification, sometimes called medication-assisted treatment, in which doctors prescribe opioid or non-opioid drugs to help the patient complete the Percodan-Demi detoxification process. Medical Percodan-Demi detoxification can occur through an outpatient clinic or at an inpatient setting.

Outpatient Percodan-Demi detoxification is appropriate for those people who have been opioid-dependent for longer than a year and who require little supervision during detoxification. People who need to work or take care of other responsibilities during the detoxification process can benefit from this treatment approach.

Patients take opioid replacement drugs, such as methadone or buprenorphine, which mimic the effects of Percodan-Demi so they stop the occurrence of withdrawal symptoms but are too weak to get the patient high. These drugs serve as an aid to the tapering process, reducing withdrawal symptoms to tolerable levels. Patients start out on high induction doses of methadone or buprenorphine then take successively smaller doses each day during the tapering phase until they no longer feel withdrawal symptoms.

Patients may also use methadone or buprenorphine as part of a drug maintenance program. Patients enrolled in a methadone maintenance program come to an approved outpatient clinic each day to drink a beverage containing this replacement drug. Buprenorphine maintenance allows for more flexibility, as doctors can now write buprenorphine prescriptions lasting a week or longer.


A previously unknown German chemist first synthesized methadone in 1939 while searching for a new opioid pain reliever. Doctors around the world still prescribe methadone to relieve pain. In the early 1960s, doctors noticed methadone reduced withdrawal symptoms in heroin addicts. In 1964, doctors used methadone to stop a heroin epidemic sweeping through New York City. The FDA approved methadone for use in the treatment of opioid dependence in 1972. Today, about 100,000 Americans use a methadone maintenance program.

Many patients use methadone as a way to reduce withdrawal symptoms during the tapering process. A physician will start the patient on 10 to 15 mg of methadone and increase the dosage upwards 10 mg each day until the patient no longer feels withdrawal symptoms. The physician will hold the patient at this induction dose for a few days before starting the tapering phase, reducing daily doses by 10 mg each day until the patient is no longer dependent on opioids.


Someone can use buprenorphine as an aid to tapering. While everyone is different, someone could use buprenorphine to complete Percodan-Demi detoxification in as little as one week, spending the first three days in the induction phase and tapering during the final four days.

A consumer places the buprenorphine tablet under his tongue where it dissolves and enters the bloodstream. It is possible to abuse buprenorphine intravenously by dissolving the tablet before injecting the medication into a vein.


Drug companies deter improper administration of buprenorphine by adding naloxone to the brand name buprenorphine preparation, Suboxone. When taken as directed under the tongue, the naloxone in Suboxone does not affect the consumer. When administered intravenously, however, naloxone interferes with buprenorphine to prevent the consumer from getting high. Additionally, intravenous administration of naloxone causes withdrawal symptoms in an opioid-dependent person.

Many local hospitals and specialty inpatient facilities now offer opioid detoxification. Inpatient care usually includes the administration of multiple non-opioid medications to reduce the wide variety of withdrawal symptoms associated with Percodan-Demi detoxification. Detoxification specialists may administer naltrexone to lower oxycodone levels and initiate the detoxification process. Doctors may give the patient hydroxyzine or promethazine to soothe nausea, Loperamide to stop diarrhea, and clonidine to ease a range of symptoms including watery eyes, restlessness, and sweating.

Nurses provide around-the-clock care and close patient supervision, promptly addressing any complications that may arise. This highly structured environment increases the likelihood the individual will avoid relapse and complete the detoxification process.

Inpatient Percodan-Demi detoxification is for anyone who wants to improve his chances of achieving an opioid-free state with powerful detoxification and anti-withdrawal medications and close patient supervision. Inpatient care is appropriate for anyone who has been unable to complete Percodan-Demi detoxification at home or through outpatient care, or who have a documented history of poor performance in less restrictive settings.

Inpatient Percodan-Demi detoxification is necessary for anyone recovering from an overdose or another condition that makes outpatient care unsafe. Anyone at risk for severe withdrawal symptoms or complications should seek inpatient care, as should those with serious psychiatric problems, such as depression with suicidal thoughts or other forms of acute psychosis. Any individual who exhibits behaviors that may cause danger to the patient himself or to others should seek inpatient care.

Rapid Opiate Detox

Rapid opiate detox is a safe and effective procedure that brings the patient to an opioid-free state in hours rather than days or weeks. Rapid detox patients receive anesthesia and sedative prior to the standard detoxification and anti-withdrawal drugs so they rest in a comfortable “twilight sleep” during the difficult detoxification process.

Rapid detox is appropriate for anyone who wants to improve his chances of successfully completing Percodan-Demi detoxification. Rapid detox is also right for anyone who cannot tolerate the demeaning and difficult detoxification process.

Our detox center: Who we are and what we do

We are a group of dedicated, board-certified anesthesiologists and other highly trained medical professionals who receive extra training in rapid detox procedures. We have helped thousands of people achieve a drug-free state since opening the doors of our fully accredited hospital more than a decade ago.

We treat our patients as people, not as drug addicts. We prescreen patients in our accredited facility to search for underlying conditions that might undermine success and develop a personalized treatment plan that fits our patient’s individual needs. After completing Percodan-Demi detoxification, patients may continue recovery in our qualified aftercare facility.

Detox Comparisons

Choosing between the different treatment options can be confusing. It is often helpful to compare the various approaches to appreciate the strengths and weaknesses of each.

Self-detoxification is usually the least expensive and most private form of treatment but, without anti-withdrawal drugs or professional consultation, self-detoxification is associated with the greatest risk for complications.

Outpatient detoxification combines opioid anti-withdrawal drugs with professional guidance to provide greater protection from withdrawal symptoms and complications than self-detoxification affords. Patients sometimes have difficulty tapering methadone or buprenorphine though, and can be in treatment for weeks or months.

Outpatient maintenance is better than self-detoxification in that it offers replacement drugs and counseling. Outpatient care reduces the risk for complications. Patients remain in treatment for months or years.

Inpatient Percodan-Demi detoxification provides the greatest amount of protection against withdrawal symptoms and complications. Inpatient care also brings the patient to an opioid-free state

Inpatient care is better because it offers complete detoxification before the individual engages in rehabilitation. Inpatient care offers more monitoring. Completion rates are highest for detoxification services - about 66 percent - and lowest for outpatient treatment at about 42 percent. Only about 14 percent of those participating in outpatient medication-assisted therapy with methadone or buprenorphine complete treatment.

The average length of stay for detoxification is 4 days, compared with 197 days for medication-assisted therapy.

Rapid detox is the most humane and efficient approach, offering fast and complete detoxification. Rapid detox brings the patient to a drug-free state in hours rather than days or months. Rapid detox frees the patient from the uncomfortable and demoralizing withdrawal symptoms that interfere with recovery.

Detox Possible Complications

The detoxification process is not usually a life-threatening procedure but complications can be dangerous. Pre-existing medical conditions and co-existing substance abuse problems increase the risk for complications, as do pregnancy and long-term or severe substance abuse.

Relapse is the primary complication associated with all forms of Percodan-Demi detoxification. Someone might take more Percodan-Demi to stop the pain of withdrawal symptoms during the detoxification process, or relapse after completing Percodan-Demi detoxification.

Relapse increases the risk for overdose, which can be fatal. In 2008, 14,800 Americans died after an overdose of Percodan-Demi or other opioid. Overdoses from prescription overdoses now kill more people in the United States than cocaine and heroin overdoses combined.

The detoxification process decreases the individual’s tolerance of opioids, making her more sensitive to the effects of oxycodone. Because of this increased sensitivity and lowered tolerance, it is possible for someone to overdose on a smaller amount of Percodan-Demi than she used to take before feeling even moderate withdrawal symptoms for a short time.

Self Detox Possible Complications

Unprotected from withdrawal symptoms, self-detoxification patients are likely to relapse. Lingering withdrawal symptoms prevent many patients from completing self-detoxification to reach an opioid-free state.

The absence of prescreening for underlying illnesses, anti-withdrawal drugs to reduce symptoms, and professional monitoring, increases the risk for complications during self-detoxification. Extreme vomiting or diarrhea can cause dehydration and imbalances in electrolytes such as potassium and sodium.

Withdrawal symptoms associated with Percodan-Demi detoxification could worsen undetected pre-existing health conditions associated with substance abuse. Without professional care, a worsened illness can lead to unexpected and potentially serious complications. For example, Percodan-Demi detoxification may increase blood pressure and pulse in a way that can worsen some heart conditions. Withdrawal may also worsen anxiety in patients already suffering from mood disorders. The detoxification process can also cause the return of pain in patients who take Percodan-Demi to relieve discomfort associated with a chronic or severe illness.

Outpatient Care Possible Complications

Outpatient care usually includes prescreening, medications and professional guidance, reducing the likelihood and severity of complications. However, complications can occur with outpatient Percodan-Demi detoxification.

The patient may grow dependent on the replacement drug and have trouble quitting methadone or buprenorphine at the appropriate time. Some individuals abuse methadone or buprenorphine, increasing the risk for overdose. The number of deaths associated with methadone overdose is increasing dramatically: in 2009, there were 5.5 times as many deaths associated with methadone as there were in 1999. Most of these deaths were due to abuse and inappropriate administration. Buprenorphine abuse and improper administration may also lead to death, especially when the individual uses buprenorphine with benzodiazepines, such as those used in The Thomas Recipe.

Inpatient Detox Possible Complications

Prescreening, anti-withdrawal drugs, and close patient supervision makes inpatient care safer than self-detoxification but complications may still occur. Someone struggling with withdrawal from multiple substances, especially alcohol, benzodiazepines, sedatives and anti-anxiety drugs, may have trouble completing the detoxification process even in an inpatient setting.

Rapid Detox Possible Complications

Rarely, someone may suffer an allergic or hypersensitivity reaction to the drugs used in rapid detox. The patient may have trouble breathing or suffer problems with blood pressure and pulse after receiving strong sedatives. Another patient might experience swelling, infection or bruising at the anesthesia administration site.

Detox Myths

Despite decades of research and clinical experience of real doctors and opioid-dependent people, the myths surrounding Percodan-Demi detoxification prevent many people from getting the help they need.

Self Detox Myths

Myth: Self-detoxification is just a matter of discipline - anyone can overcome Percodan-Demi dependence with enough determination.
Fact: While willpower helps someone refuse drugs when offered, Percodan-Demi detoxification is an intense physiological process that sometimes requires the help of a physician.

Myth: Anti-withdrawal drugs make home remedies like The Thomas Recipe safe and effective.
Fact: Combining prescription and non-prescription medications can result in dangerous drug interactions, especially with high levels of opioids in the system. Only a doctor has the medical education and legal power to prescribe safe and effective medications.

Outpatient Detox Myths

Myth: It is cheaper to let opioid-dependent people “dry out” in jail than to provide treatment.
Fact: One year of imprisonment costs about $24,000 per prisoner; that same year of methadone costs an average of $4,700 per patient.

Myth: Methadone rots your bones.
Fact: Inadequate methadone may cause withdrawal symptoms such as bone ache.

Inpatient Detox Myths

Myth: Treating opioid dependence is useless because it is a chronic condition with no hope of recovery.
Fact: Relapse rates for drug addiction are similar to those of other chronic diseases, such as high blood pressure, diabetes or asthma, about 40 to 60 percent. Inpatient detoxification helps patients complete the detoxification process and avoid relapse.

Myth: Communities cannot afford to spend money on drug treatment programs right now.
Fact: Communities cannot afford to ignore the savings drug treatment brings. Experts estimate every dollar spent on drug treatment programs returns a yield between $4 and $7 in reduced drug-related crime rates and the associated costs to the criminal justice system. Add in savings to the local healthcare system and these savings rise to $12 gained for every dollar invested.

Rapid Detox Myths

Myth: Pain and humiliation are important aspects of Percodan-Demi detoxification - they serve as punishment for becoming opioid-dependent.
Fact: Suffering is never an appropriate part of any medical treatment plan. In fact, the uncomfortable and demoralizing aspects of Percodan-Demi detoxification sometimes prevent patients from completing the process. Rapid detox is the most humane and efficient approach to medical detoxification in that rapid detox patients rest in a comfortable state for a few hours during the process, rather than struggling for days or weeks to reach an opioid-free state.

Myth: It takes weeks or months to complete Percodan-Demi detoxification.
Fact: A reputable expert can perform rapid detox in one to two hours.

Detox and Pregnancy
An opioid-dependent woman is more likely to suffer from certain conditions than a non-dependent woman is, including anemia, blood infections, pneumonia, mood disorders, heart conditions, and hepatitis. Opioid dependence increases the risk someone will contract and spread infectious diseases, including sexually transmitted diseases, tuberculosis, and HIV/AIDS.

These conditions increase the risk for complications for women and their unborn babies during pregnancy, labor and delivery. The mother may hemorrhage and experience uncontrolled bleeding, for example, or have separation or inflammation of the tissues surrounding the baby, slowed fetal growth premature labor and delivery, spontaneous abortion, and fetal death.

The underlying conditions associated with opioid dependence and the complications they may cause in during pregnancy makes Percodan-Demi detoxification risky for pregnant women and the babies they carry. Methadone reduces these complications. Methadone maintenance is currently the only approved approach to treating opioid dependence in pregnant women. Babies born to women taking methadone during pregnancy will remain under close inpatient observation for the first 72 hours.

A baby born to a mother who takes Percodan-Demi or methadone regularly may suffer neonatal abstinence syndrome, or NAS. A baby with NAS may be born opioid-dependent and suffer withdrawal symptoms during the first weeks or months of life. NAS may also cause the baby to suffer from low birth weight, breathing problems, difficulty feeding, seizures, or even death.

Self Detox and Pregnancy

Self-detoxification can be risk for a pregnant woman and her unborn baby. A pregnant woman should consult a physician before weaning herself from Percodan-Demi.

Outpatient and Pregnancy

A pregnant woman can start methadone maintenance as an outpatient. In the early stages, she will visit the clinic twice daily - once to receive her morning methadone dose and again in the evening to undergo a medical evaluation that helps doctors determine the next morning’s dose. Doctors usually start pregnant women on 10 to 20 mg of methadone daily and increase dosages by 5 to 10 mg a day until finding a safe dose that covers symptoms, with a maximum daily dosage of 60 mg. Some women experience breakthrough withdrawal symptoms towards the end of pregnancy and require stronger doses.

Inpatient and Pregnancy

Many opioid-dependent pregnant women choose to start methadone maintenance as inpatients, with a typical hospital stay lasting about three days. Inpatient care makes it easier for doctors to evaluate the mother’s response to dosages and use fetal monitoring equipment to monitor how well the baby is tolerating treatment.

Opiate detox symptoms

Percodan-Demi detoxification usually causes withdrawal symptoms that appear in two phases. Initially, the patient may feel agitated, anxious and have trouble sleeping. He may also have muscle aches, watery eyes, a runny nose, and seem to perspire and yawn excessively. Later, he may develop stomach cramps, diarrhea, nausea, and vomiting. His pupils may dilate and become large, and he might have goose bumps on his skin. These symptoms fade as he completes Percodan-Demi detoxification.

What is the best method to detox from this drug?
Each person experiences dependence on Percodan-Demi and recovery from this chronic condition in a slightly different way, so no single treatment plan is right for everyone. A treatment plan choice depends largely on personal needs, reflecting the individual’s ability to refrain from substance abuse and his need for flexibility. Someone who is dependent on Percodan-Demi should choose the least restrictive form of treatment that is still likely to provide safe and effective care.



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