Dazidox

Uses

Generic Name or Active Ingridient: Oxycodone.

Physicians prescribe Dazidox to treat moderate to severe pain. Dazidox is a brand name formulation of the opioid pain reliever, oxycodone. Oxycodone is a commonly prescribed opiate in the United States, according to the Drug Enforcement Administration, or DEA. In 2008, pharmacies filled more than 50 million oxycodone prescriptions. Learn More About Dazidox Uses

Other, off label uses for this medicine

The oxycodone in Dazidox is also used alone or with other antitussives to relieve a dry, non-productive cough. Other off label uses for the opiate pain reliever Dazidox may exist. More Off-Label Uses for Dazidox

Administration/Dosage

Dazidox is available in immediate- and extended-release formulas. Manufacturers make Dazidox as a tablet, liquid concentrate or solution.

Dosage varies between patients. Physicians typically suggest a patient take 5 to 15 mg of immediate-release Dazidox every 4 to 6 hours as needed for pain. Doctors prescribe an initial dose of 10 mg of extended-release Dazidox every 12 hours and increase the dosage as needed.

A pediatrician will determine the best strength and dosing schedule for a child.

The consumer should take the immediate-release formula of Dazidox only when needed for pain, so missed doses are not an issue for these patients. Those who use the extended-release formula of Dazidox should take this medication every 12 hours, even in the absence of pain. If an extended-release user misses a dose, she should take the missed dose as soon as possible. If it is nearly time to take another regularly scheduled dose, skip the missed dose and resume the normal schedule. Do not double up on doses in an effort to catch up.

Measure each dose of liquid Dazidox with a special dose-measuring spoon or cup. Do not use a household tablespoon to dispense liquid medicine, as this increases the risk for dosing errors and overdose.

If you have been taking Dazidox for a long time, or have been taking high doses of this opioid, you may suffer withdrawal symptoms when you stop taking the medication. Try weaning yourself off by increasing the amount of time between doses.

Read More About Dazidox Administration and Dosage

Action

The active ingredient in Dazidox, oxycodone, binds to the receptor cells in the brain and nervous system in a way that changes how the brain perceives pain. Oxycodone also acts directly on the cough center of the brain to reduce the urge to cough.

More About How Dazidox Works

Precautions

Tell your doctor if you are allergic to oxycodone or other opioids, such as morphine or codeine. An allergic reaction is a serious medical condition that requires the immediate attention of a medical professional. Immediately discontinue Dazidox and seek out medical care upon the first sign of an allergic reaction.

Symptoms of an allergic reaction include hives, rash, itching and swelling of the face, lips, tongue or throat.

Talk with your doctor about your medical history. Certain illnesses may interfere with the way Dazidox works; this medication may worsen your condition or hinder treatment.

Tell your physician about any significant illnesses or conditions that you currently have or have a history of, including:

  • Addison's Disease
  • Alcohol Abuse
  • Brain Tumor
  • Breathing Problems
  • Cancer of the Esophagus or Colon
  • Central Nervous System Depression
  • Chronic Obstructive Pulmonary Disease
  • Curvature of the Spine With Breathing Problems
  • Drug Dependence, Especially with Opioids
  • Enlarged Prostate
  • Gallbladder Disease
  • Gallstones
  • Head Injuries
  • Heart Condition Known as Cor Pulmonale
  • High Carbon Dioxide in the Blood
  • Kidney Disease
  • Liver Disease
  • Low Blood Pressure
  • Low Blood Volume
  • Mental Illness including Psychosis
  • Pancreatitis
  • Paralytic Ileus: A Digestive Condition in Which the Intestine Stops Working
  • Respiratory Depression
  • Seizures
  • Severe Asthma
  • Trouble With Swallowing
  • Underactive Thyroid
  • Urinary Problems
  • Weakened Physical Condition: May Increase Risk for More Serious Side Effects.

Severe kidney and liver disease may slow the rate at which the body processes and removes Dazidox, increasing the risk for side effects or overdose.

Dazidox can cause drowsiness. Do not operate heavy machinery, drive a car or perform potentially dangerous tasks until you know how Dazidox affects you.

Do not drink alcohol or use other pain relievers while taking Dazidox. Doing so may result in serious drug interactions and side effects, including death.

Dazidox can be habit forming. Take only as directed. Do not take Dazidox in amounts larger than prescribed. Do not use this opioid longer than directed.

Dazidox can cause constipation. Drink six to eight full glasses of water each day to soften your stool. Speak with your doctor or nutritionist about ways to increase your dietary fiber and reduce constipation. Do not take stool softeners or laxatives unless directed to do so by your doctor.

Read More About Dazidox Precautions

Warnings

Certain prescription and over the counter medications can add to sleepiness caused by Dazidox, or could even slow down your breathing in a dangerous condition doctors call respiratory depression. Avoid taking new prescription and over the counter drugs while on Dazidox. Tell your doctor if you are taking or plan to take cold or allergy medicine, narcotic pain medicine, sleeping pills, muscle relaxers, antidepressants or seizure medication.

Dazidox and other medications containing oxycodone may cause damage to unborn babies. Do not take Dazidox if you are pregnant or plan to become pregnant while taking this opioid painkiller. Taking this medication while pregnant may cause your infant to suffer breathing problems along with symptoms of dependency and withdrawal, a condition known as neonatal abstinence syndrome. Dazidox may pass into breast milk; do not breastfeed your baby while taking Dazidox.

You may experience withdrawal symptoms if you suddenly stop taking Dazidox, especially if you have been taking high doses or using this opioid painkiller for a long time. Speak with your doctor if you feel unpleasant withdrawal symptoms when you skip a dose; she will develop a plan to help you wean yourself from Dazidox. If you are unable to wean yourself slowly from Dazidox, your physician may recommend a treatment program.

More Warnings About Using Dazidox

Drug Interactions

Tell the prescribing physician and pharmacist filling the order about all your medications, including prescriptions, over-the-counter drugs, vitamins or herbal remedies. Dazidox may interact with these substances in unintended or unsafe ways. Dazidox may interfere with the way these medications work, or these drugs may change how your body handles Dazidox.

Dazidox may interact with the following medications:

  • Acetophenazine
  • Adinazolam
  • Alfentanil
  • Alprazolam
  • Amobarbital
  • Anileridine
  • Aprobarbital
  • Atazanavir
  • Brofaromine
  • Bromazepam
  • Brotizolam
  • Buprenorphine
  • Buspirone
  • Butabarbital
  • Butalbital
  • Butorphanol
  • Carisoprodol
  • Chloral Hydrate
  • Chlordiazepoxide
  • Chlorpromazine
  • Chlorzoxazone
  • Clarithromycin
  • Clobazam
  • Clonazepam
  • Clorazepate
  • Clorgyline
  • Codeine
  • Dantrolene
  • Desflurane
  • Dexmedetomidine
  • Dezocine
  • Diazepam
  • Diphenhydramine
  • Doxylamine
  • Enflurane
  • Erythromycin
  • Escitalopram
  • Estazolam
  • Eszopiclone
  • Ethchlorvynol
  • Ethopropazine
  • Fentanyl
  • Flumazenil
  • Flunitrazepam
  • Fluphenazine
  • Flurazepam
  • Fluvoxamine
  • Fospropofol
  • Furazolidone
  • Halazepam
  • Halothane
  • Oxycodone
  • Hydromorphone
  • Hydroxyzine
  • Indinavir
  • Iproniazid
  • Isocarboxazid
  • Isoflurane
  • Itraconazole
  • Ketamine
  • Ketazolam
  • Ketoconazole
  • Lazabemide
  • Levorphanol
  • Linezolid
  • Lorazepam
  • Lormetazepam
  • Medazepam
  • Meperidine
  • Mephenesin
  • Mephobarbital
  • Meprobamate
  • Mesoridazine
  • Metaxalone
  • Methdilazine
  • Methocarbamol
  • Methohexital
  • Midazolam
  • Moclobemide
  • Morphine
  • Morphine Sulfate Liposome
  • Nalbuphine
  • Nefazodone
  • Nelfinavir
  • Nialamide
  • Nitrazepam
  • Nitrous Oxide
  • Nordazepam
  • Opium
  • Oxazepam
  • Oxycodone
  • Oxymorphone
  • Pargyline
  • Pentazocine
  • Pentobarbital
  • Perphenazine
  • Phenelzine
  • Phenobarbital
  • Prazepam
  • Procarbazine
  • Prochlorperazine
  • Promazine
  • Promethazine
  • Propiomazine
  • Propofol
  • Propoxyphene
  • Quazepam
  • Ramelteon
  • Rasagiline
  • Remifentanil
  • Ritonavir
  • Saquinavir
  • Secobarbital
  • Selegiline
  • Sertraline
  • Sevoflurane
  • Sodium Oxybate
  • Sufentanil
  • Tapentadol
  • Telithromycin
  • Temazepam
  • Thiethylperazine
  • Thiopental
  • Thioridazine
  • Toloxatone
  • Tranylcypromine
  • Triazolam
  • Trifluoperazine
  • Triflupromazine
  • Trimeprazine
  • Zaleplon
  • Zolpidem

Taking any of the following medications while using Dazidox increases the risk for side effects:

  • Miconazole
  • Rifampin
  • St John's Wort
  • Voriconazole

More Dazidox Drug Interactions

Side effects

Most people do not suffer side effects while taking Dazidox but, like all medications, this opioid painkiller may cause adverse reactions. Most side effects are not serious and go away on their own with continued use. If you experience non-serious side effects, continue taking Dazidox but consult with the prescribing physician if your side effects become intolerable or do not disappear.

The most common and not serious side effects include: Constipation Drowsiness Loss of Strength Relaxed and Calm Feeling Sleepiness Unusual Drowsiness

Less commonly, consumers experience these non-serious side effects:

  • Abnormal Dreams
  • Acid or Sour Stomach
  • Anxiety
  • Belching
  • Burning Feeling in the Chest or Stomach
  • False or Unusual Sense of Well-Being
  • Heartburn
  • Hiccups
  • Indigestion
  • Nervousness
  • Sleeplessness
  • Stomach Discomfort, Upset or Pain
  • Tenderness in the Stomach Area
  • Trouble With Sleeping
  • Unable To Sleep
  • Weight Loss

Some side effects are serious, requiring the attention of a medical professional. Immediately discontinue Dazidox and seek medical help for serious side effects, including:

  • Chills
  • Cold Sweats
  • Confusion
  • Difficult or Labored Breathing
  • Dizziness, Faintness, or Lightheadedness When Getting Up Suddenly From a Lying or Sitting Position
  • Fever
  • Shortness of Breath
  • Tightness in the Chest
  • Twitching
  • Wheezing

Other rare but serious side effects may occur. Contact a physician immediately if you experience the following adverse reactions after taking Dazidox:

  • Abdominal or Stomach Pain
  • Bloating or Swelling of the Face, Arms, Hands, Lower Legs or Feet
  • Blood in the Urine
  • Burning While Urinating
  • Burning, Crawling, Itching, Numbness, Prickling, "Pins and Needles" or Tingling Feelings
  • Chest Pain
  • Convulsions
  • Cough
  • Decrease in the Frequency of Urination
  • Decrease in Urine Volume
  • Decreased Urine Output
  • Difficult or Painful Urination
  • Difficulty in Passing Urine (Dribbling)
  • Difficulty With Swallowing
  • Dizziness
  • Dry Mouth
  • Fainting
  • Fast or Irregular Heartbeat
  • Fast, Irregular, Pounding, or Racing Heartbeat or Pulse
  • Feeling of Warmth or Heat
  • Flushing or Redness of the Skin, Especially on the Face and Neck
  • Frequent Urination
  • Headache
  • Hives
  • Increase in Heart Rate
  • Increased Thirst
  • Increased Volume of Pale, Dilute Urine
  • Itching
  • Lightheadedness
  • Muscle Pain or Cramps
  • Nausea or Vomiting
  • Puffiness or Swelling of the Eyelids or Around the Eyes, Face, Lips or Tongue
  • Rapid Breathing
  • Rapid Weight Gain
  • Severe Constipation
  • Severe Vomiting
  • Shakiness in the Legs, Arms, Hands or Feet
  • Skin Rash
  • Sunken Eyes
  • Sweating
  • Swelling or Puffiness of the Face
  • Swollen, Painful, or Tender Lymph Glands in the Neck, Armpit or Groin
  • Thirst
  • Tingling of the Hands or Feet
  • Trembling or Shaking of the Hands or Feet
  • Unusual Tiredness or Weakness
  • Unusual Weight Gain or Loss
  • Wrinkled Skin

Learn More About Dazidox Side Effects

Overdose

Overdose of Dazidox is a serious medical situation. If you suspect that you or someone you know has taken an overdose of Dazidox, contact your local emergency room or poison control center by calling 1-800-222-1222.

Symptoms of overdose include:

  • Cold, Clammy Skin
  • Circulatory Collapse
  • Stupor
  • Coma
  • Depression
  • Respiratory Depression
  • Cardiac Arrest
  • Death

Learn More About Dazidox Overdose

Abuse

Recreational users target Dazidox for the euphoric effects associated with oxycodone. The DEA reports oxycodone abuse has escalated dramatically in recent years, even among school-age children. Abusers use diversion tactics, like placing bogus call-in prescriptions to pharmacies, altering prescriptions, theft and illicit purchases from the internet, to gain Dazidox.

Oxycodone pills are the most frequently abused form of the opioid; pills are often taken with alcohol to maximize effect. There is increased potential for abuse by a significant segment of the population largely because this drug is widely available to people of all age groups and is viewed as generally safe by the medical community.

Oxycodone carries a high risk for opioid dependence and addiction requiring treatment.

Read More About Dazidox Abuse

Withdrawal

Withdrawal symptoms occur if you have developed a dependence on Dazidox and suddenly stop taking the medication. Withdrawal symptoms may be severe enough to prevent detoxification without medical intervention. Withdrawal symptoms usually begin six to twelve hours after your last dose and peak 24 to 72 hours later. These symptoms are very unpleasant and typically last five or more days, with the worst symptoms appearing on or about the fourth day.

Withdrawal symptoms include:

  • Chills
  • Depression
  • Diarrhea
  • Dilated Pupils
  • Fevers
  • Insomnia
  • Intense Cravings for the Drug
  • Irritability
  • Muscle Aches
  • Nausea or Vomiting
  • Runny Nose or Eyes
  • Sweating
  • Yawning

Detox

Substance abuse programs usually include detoxification from the effects of Dazidox and behavioral counseling to help individuals learn how to live without opioids. Rapid detox is a humane way to get through the peak discomfort associated with withdrawal. During rapid detox, board certified anesthesiologists administer a combination of sedatives and anesthesia, so that you sleep while medical professionals cleanse dangerous opioids from your system. You awaken refreshed a few hours later, unaware of the unpleasant withdrawal process associated with Dazidox. Other types of treatment plans are effective, whether you choose an inpatient facility or an outpatient program. Consult with your physician to find out the most effective treatment plan. Learn More About Dazidox Detoxification Programs

Storage

Keep Dazidox in a secure location away from excessive heat and moisture. Count your pills frequently and keep track of how many you should have. Keep Dazidox away from children, pets and adults who might take this drug accidentally or on purpose. Never share Dazidox with others.

When finished with your Dazidox prescription, flush unused medication down the toilet. Dispose of any liquid Dazidox formula more than 90 days old. Do not throw this medication in the general trash, where children, pets and drug abusers can access it. Ask your pharmacist how to dispose of Dazidox and other medications if you are unsure or are concerned that someone in your household may abuse leftover Dazidox.

Read More About Storing Dazidox

Miscellaneous Information

According to the U.S. Drug Enforcement Agency, or DEA, drugs containing oxycodone sold for an average of $1 per milligram. The 40 mg extended-release counterpart of Dazidox, OxyContin, was the most popular among illicit users. This means abusers were paying $40 per tablet.

In 2008, 13.8 million people aged 12 or older used drugs containing the active ingredient in Dazidox, oxycodone, for nonmedical use at least once during their lifetime.

Our Treatment Center

Facts

  • Dazidox

Programs