Codeine, Acetaminophen and Chlorpheniramine

  • Generic Name or Active Ingridient: Codeine
Drug Class: Codeine, Acetaminophen And Chlorpheniramine > Codeine > Opiate > Opioids > Opioid Agonist > Analgesic.

Uses

Doctors prescribe codeine, acetaminophen and chlorpheniramine combination products to ease symptoms associated with the common cold, hay fever and upper respiratory allergies. These symptoms include cough, sneezing, runny nose and itchy, watery eyes.

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Administration/Dosage

Codeine, acetaminophen and chlorpheniramine combination products are sold under the brand name, Cotabflu.

Take codeine, acetaminophen and chlorpheniramine preparations with food or milk if this medication upsets your stomach.

Codeine, acetaminophen and chlorpheniramine preparations are available in tablet form. Dosage Children and elderly

Codeine, acetaminophen and chlorpheniramine combination products are typically prescribed to be taken only as needed to relieve symptoms rather than on a regular schedule, so missing doses is not normally a problem. Simply take another dose when you need to relieve cough, stuffy nose and watery, itching eyes, providing enough time has passed since your last dose. If your doctor has prescribed this medication to be taken on a strict schedule and you miss a dose, take another dose as soon as you remember. If it is nearly time to take another dose and you can tolerate the runny nose, watery eyes and coughing, skip the missed dose and resume your normal schedule.

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Action

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Precautions

Tell your doctor if you are allergic to any component of codeine, acetaminophen and chlorpheniramine preparations or to any other medications. Allergic reaction is a serious medical condition that may deteriorate into a life-threatening event quickly and without warning. Seek immediate medical care if you experience symptoms of an allergic reaction after taking codeine, acetaminophen and chlorpheniramine combination drugs.

Symptoms of an allergic reaction include hives, itchiness, rashes and watery eyes. Symptoms of a severe reaction may include abdominal pain, difficulty breathing, anxiety, feeling lightheaded or nausea and vomiting.

Codeine, acetaminophen and chlorpheniramine preparations may cause your skin to be more sensitive to sunlight. Avoid prolonged exposure to natural sunlight or UV exposure associated with tanning beds; sunburn may result. Wear protective clothing and sunscreen with a minimum SPF of 15 whenever you expect to be out in the sun.

Medical History Tell your doctor about any serious or chronic illnesses including

Codeine, acetaminophen and chlorpheniramine products can make you sleepy or impair your thinking and slow down your reactions. Do not operate heavy machinery, drive a car or engage in risky behavior until you know how codeine, acetaminophen and chlorpheniramine products affect you. Be careful performing any tasks that require you to make quick decisions.

Avoid drinking alcohol when taking codeine, acetaminophen and chlorpheniramine preparations. Alcohol can increase side effects associated with codeine and chlorpheniramine. Consuming alcohol also increases your risk for liver damage caused by taking acetaminophen. If you drink more than three alcoholic beverages per day, do not use acetaminophen without your doctor's consent and never take more than 2000 mg of acetaminophen per day.

Chlorpheniramine may interfere with some allergy tests. Tell your doctor or allergist that you are taking an antihistamine before you participate in allergy screening. They may request you stop taking codeine, acetaminophen and chlorpheniramine preparations before administering the allergy test.

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Warnings

Pregnancy

Codeine is excreted in breast milk. Do not take codeine, acetaminophen and chlorpheniramine while breastfeeding.

Do not stop taking codeine, acetaminophen and chlorpheniramine suddenly unless your doctor tells you to do so. Sudden cessation may cause withdrawal symptoms, especially if you have been taking high doses or using codeine, acetaminophen and chlorpheniramine for a long time. If you feel withdrawal symptoms when you don't take this medication, try weaning yourself from codeine, acetaminophen and chlorpheniramine preparations by taking increasingly smaller doses further apart. Talk with your physician or consult with a rehabilitation specialist if severe withdrawal prevents you from quitting codeine, acetaminophen and chlorpheniramine use.

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Drug Interactions

Do not take codeine, acetaminophen and chlorpheniramine if you have taken an MAO inhibitor in the past 14 days. You may experience serious, even life-threatening side effects if you take codeine, acetaminophen and chlorpheniramine preparations while an MAO inhibitor is still in your system. MAO inhibitors include the brand name medications Marplan, Nardil, Azilect, Eldepryl, Emsam and Parnate.

Give your pharmacist and physician a complete and current list of all your medications, including prescriptions, over-the-counter drugs and herbal remedies. Some medications might interact with codeine, acetaminophen and chlorpheniramine preparations in unsafe or unfavorable ways. Your doctor may choose a different medication or change the dosage of your codeine, acetaminophen and chlorpheniramine prescription.

Let your doctor know if you are taking medications that make you sleepy, such as narcotic pain medicine, sleeping pills, muscle relaxers and medications for seizures, depression or anxiety. Codeine, acetaminophen and chlorpheniramine may interact with these drugs in a way that makes you even sleepier.

It is especially important to tell your doctor if you are taking: methyldopa (Aldomet);

mecamylamine (Inversine);

reserpine;

a barbiturate such as amobarbital (Amytal), butabarbital (Butisol), mephobarbital (Mebaral), secobarbital (Seconal), or phenobarbital (Solfoton); or

an antidepressant such as amitriptyline (Elavil), clomipramine (Anafranil), imipramine (Janimine, Tofranil), and others.

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Side effects

Codeine, acetaminophen and chlorpheniramine may cause mild to moderate side effects. Contact your doctor if these side effects become severe, uncomfortable or don't go away after a few days. Common side effects include: dry eyes, blurred vision; dry mouth, upset stomach, constipation; warmth, tingling, or redness under your skin; dizziness, drowsiness; restless or excitability (especially in children); constipation; headache; increased sweating; or mild skin rash or itching.

There are some serious, even life-threatening side effects associated with codeine, acetaminophen and chlorpheniramine preparations. Seek medical assistance immediately if you experience severe side effects such as: severe weakness, dizziness, anxiety, restless feeling, or nervousness; confusion, hallucinations, unusual thoughts or behavior; seizure (convulsions); chest pain or tightness; fast, pounding, or uneven heartbeats; slow heart rate, weak pulse, fainting, weak or shallow breathing; signs of infection such as fever, sore throat, flu symptoms, easy bruising or bleeding (nosebleeds, bleeding gums); urinating less than usual or not at all; or nausea, stomach pain, low fever, loss of appetite, dark urine, clay-colored stools, jaundice (yellowing of the skin or eyes).

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Overdose

You can overdose on any component of codeine, acetaminophen and chlorpheniramine combination products, especially if you take large doses of this preparation or you take other medications that include codeine, acetaminophen and chlorpheniramine. An overdose of codeine can be fatal. Check the labels of all prescription and over-the-counter medications to find out if they contain codeine, acetaminophen or chlorpheniramine. Acetaminophen, also known as APAP, is a common ingredient in many preparations. Do not exceed 4000 mg of acetaminophen in a 24 hour period. If you drink more than three alcoholic beverages in a day, do not consume more than 2000 mg daily. Consult your pharmacist if you are uncertain whether a product contains acetaminophen. Call 1-800-222-1222 immediately, or contact your local emergency room, if you suspect that you or someone you know has taken an overdose of this or any other medication. Overdose is a serious, life-threatening medical condition that can deteriorate quickly and without warning. Overdose symptoms include: dizziness, drowsiness, nausea, vomiting, stomach pain, loss of appetite, increased sweating, pinpoint pupils, confusion, cold and clammy skin, blue-colored lips or fingernails, weak pulse, shallow breathing, seizure (convulsions), fainting, or breathing that stops.

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Abuse

The euphoric feeling people get from codeine makes this drug attractive for recreational use. People who use codeine recreationally are at higher risk for developing dependence and addiction but it is also possible for medical patients to become inadvertently dependent on prescription pain medicine. In an attempt to predict a drug's risk for dependence and addiction, the United States Drug Enforcement Administration classifies drugs into various schedules. Codeine is currently a Schedule II drug, which means it is associated with a high potential for abuse which may lead to severe psychological or physical dependence. Illicit users obtain codeine, acetaminophen and chlorpheniramine by forging prescriptions, calling in bogus orders to pharmacies, going to multiple doctors or by stealing it from friends and family. Codeine is also widely available on the street.

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Withdrawal

Withdrawal symptoms are a normal, predictable side effect of using narcotics to control pain and not necessarily a sign that someone is using drugs illegally. Withdrawal symptoms can be an extremely unpleasant experience; sometimes severe withdrawal symptoms can prevent a person from successfully overcoming their dependence on drugs. Tell your doctor if you cannot stop taking codeine, acetaminophen and chlorpheniramine on your own. She may recommend you seek the help of a qualified rehabilitation professional. Withdrawal symptoms include:

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Detox

Detoxifying your body from codeine, acetaminophen and chlorpheniramine is a complex medical procedure that requires thoughtful attention from rehabilitation specialists. The success of your rehabilitation depends on addressing your individual medical, psychological and social needs. The most advanced and humane rehabilitation treatment option today is rapid detox, where you are sedated during the withdrawal period. During this procedure, physicians administer anesthesia along with other medicines to facilitate rapid detoxification of codeine, acetaminophen and chlorpheniramine from your body while you sleep. You will not remember the withdrawal process and you will awaken free of your physical dependence on codeine, acetaminophen and chlorpheniramine. After the detoxification process, specially trained doctors, nurses and counselors help you regain your physical and mental strength through counseling and other social services. Other rehabilitation options are available to help you stop using codeine, acetaminophen and chlorpheniramine. Talk with your doctor or contact a qualified rehabilitation center.

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Storage

Keep codeine, acetaminophen and chlorpheniramine preparations at temperatures between and degrees Fahrenheit, away from excessive moisture and light. Do not store codeine, acetaminophen and chlorpheniramine preparations in your bathroom or car. Keep this medicine in a tightly sealed container, away from children and pets. Put this medicine where adults cannot take it by accident or on purpose. Dispose of codeine, acetaminophen and chlorpheniramine preparations when you no longer need it or when your physician tells you to stop taking it. Talk with your doctor or pharmacist about the best way to dispose of unused doses of codeine, acetaminophen and chlorpheniramine preparations. Do not flush it down the toilet unless your pharmacist or physician instructs you to do so.

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Miscellaneous information

Miscellaneous Information About Codeine, Acetaminophen and Chlorpheniramine